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Fibrous Dysplasia

If you have ever been diagnosed with a bone disorder, you may be familiar with fibrous dysplasia. This condition is a rare bone disorder that can cause problems with the growth and development of bones. Fibrous dysplasia is basically a condition in which there is abnormal growth of fibrous tissue in the bones. This condition can affect any bone in the body, but most commonly affects the long bones in the arms and legs, such as the femur or tibia. Fibrous dysplasia can cause pain, deformity, and fractures. Fibrous dysplasia is a rare bone disorder that occurs when the bone-forming cells do not function properly. This can cause the bones to be weak and deformities can develop.


Most Commonly Affected Bones

  • Ribs

  • Skull

  • Pelvis

  • Facial bones

  • Vertebrae (spine)

  • Tibia or Shinbone

  • Femur i.e. the thighbone

  • Humerus or the Upper arm bone


Causes

Fibrous Dysplasia is a condition that affects the bones. The cause of fibrous dysplasia is unknown, but it is believed to be a genetic condition related to a genetic mutation. In most cases, the disorder is caused by a mutation in the gene that controls the bone-forming cells. This gene is called the GNAS1 gene. The GNAS1 gene is responsible for making a protein called G proteins. G proteins are involved in many cell processes, including cell growth and differentiation.


Symptoms

Symptoms of fibrous dysplasia can vary depending on the severity of the condition. So, as per the specific condition, Fibrous Dysplasia can cause a variety of symptoms, including pain, deformity, fractures, and “rubberiness” of the affected bones. So, the most common symptoms include the following:

  • Pain

  • Fractures

  • Brittle bones

  • Bone deformities

  • Uneven bone growth

Diagnosis

Fibrous Dysplasia is typically diagnosed with a combination of medical history, physical examination, and imaging tests. An x-ray would be the 1st test that is suggested. A bone biopsy may also be done to confirm the diagnosis.


Treatment Options

There is no such perfect cure for fibrous dysplasia. However, some treatment options for Fibrous Dysplasia may include pain relief, physical therapy, surgery, radiation therapy, and medication. Treatment would usually be intended to manage your symptoms & prevent any complications. Specific treatment option best suited in your case would be determined by based on the following criteria:

  • Age

  • Medical history

  • Overall health

  • Disease extent

  • Medicine tolerance

  • Patient’s opinion(s) and/or preference(s)

  • Tolerance of certain procedures and/or therapies

  • Expectations from the treatment course for this disease


Key Points

Some key points for Fibrous Dysplasia are as follows:

  • This problem can usually occur even in children (3 years to 15 years), but this might not be diagnosed till adulthood.

  • Fibrous dysplasia is a condition in which there is abnormal growth of fibrous tissue in the bones.

  • The actual cause is till date not known.

  • Symptoms of fibrous dysplasia can vary depending on the bones affected.

1Health Medical Center Can Guide You Well about Fibrous Dysplasia

Fibrous Dysplasia is a condition in which the bones become weakened and deformed. If you are looking for the best treatment options for Fibrous Dysplasia, then you must get in touch with the expert medical panel of 1Health Medical Center.


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